| Subepithelial connective tissue graft with growth factor for the treatment of maxillary gingival recession defects. | |
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MedLine Citation:
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PMID: 23342346 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Gingival recession is a challenging defect for clinicians to treat effectively. A number of recent systematic reviews have identified the connective tissue graft (CTG) in combination with coronally advanced flaps (CAFs) as the most consistently effective treatment for Miller Class I and II defects across all outcome measures. Recent advances in recombinant growth factor technology may provide opportunities for improved outcomes in conjunction with CAF + CTG procedures. In this prospective consecutive case series, recombinant human platelet-derived growth factor BB (rhPDGF-BB) was combined with CTGs for the treatment of Miller Class I or II gingival recession defects. Improved outcomes were seen for keratinized tissue gains and percent root coverage at 6 months postsurgery when compared to historic norms. All other outcome parameters appeared equivalent between the two treatment approaches. The addition of rhPDGF-BB appeared to improve early wound healing as well. |
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Authors:
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Robert P Rubins; Paul N Tolmie; Kenneth T Corsig; Eric N Kerr; David M Kim |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The International journal of periodontics & restorative dentistry Volume: 33 ISSN: 0198-7569 ISO Abbreviation: Int J Periodontics Restorative Dent Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-01-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200894 Medline TA: Int J Periodontics Restorative Dent Country: United States |
Other Details:
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Languages: eng Pagination: 43-50 Citation Subset: D |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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