Document Detail

Subepithelial connective tissue graft with growth factor for the treatment of maxillary gingival recession defects.
MedLine Citation:
PMID:  23342346     Owner:  NLM     Status:  In-Data-Review    
Gingival recession is a challenging defect for clinicians to treat effectively. A number of recent systematic reviews have identified the connective tissue graft (CTG) in combination with coronally advanced flaps (CAFs) as the most consistently effective treatment for Miller Class I and II defects across all outcome measures. Recent advances in recombinant growth factor technology may provide opportunities for improved outcomes in conjunction with CAF + CTG procedures. In this prospective consecutive case series, recombinant human platelet-derived growth factor BB (rhPDGF-BB) was combined with CTGs for the treatment of Miller Class I or II gingival recession defects. Improved outcomes were seen for keratinized tissue gains and percent root coverage at 6 months postsurgery when compared to historic norms. All other outcome parameters appeared equivalent between the two treatment approaches. The addition of rhPDGF-BB appeared to improve early wound healing as well.
Robert P Rubins; Paul N Tolmie; Kenneth T Corsig; Eric N Kerr; David M Kim
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of periodontics & restorative dentistry     Volume:  33     ISSN:  0198-7569     ISO Abbreviation:  Int J Periodontics Restorative Dent     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200894     Medline TA:  Int J Periodontics Restorative Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  43-50     Citation Subset:  D    
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