Document Detail

Subcutaneous heparin-induced thrombocytopenia.
MedLine Citation:
PMID:  708169     Owner:  NLM     Status:  MEDLINE    
Two patients developed severe and symptomatic thrombocytopenia which was clearly related to the every-12-hour subcutaneous administration of heparin sodium. One patient died of hemorrhage while the other patient's platelet count normalized after withdrawal of the therapy. The literature reveals 27 cases of significant thrombocytopenia associated with intravenous heparin administration. In light of the increasing use of low-dose subcutaneous heparin therapy it is important to recognize that this side effect may occur. Periodic platelet counts are recommended for these patients.
W J Hrushesky
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  138     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1978 Oct 
Date Detail:
Created Date:  1978-12-20     Completed Date:  1978-12-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1489-91     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Cell Count
Blood Platelets
Heparin / administration & dosage,  adverse effects*
Injections, Subcutaneous
Thrombocytopenia / chemically induced*
Reg. No./Substance:

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