Document Detail


Subcutaneous fat necrosis and whole-body cooling therapy for neonatal encephalopathy.
MedLine Citation:
PMID:  23187641     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Whole-body cooling, or therapeutic hypothermia, is increasingly becoming the standard of treatment for moderate to severe neonatal encephalopathy because it reduces neurodevelopmental disabilities and mortality in term neonates. Subcutaneous fat necrosis (SCFN) of the newborn has been identified as a potential side effect of birth asphyxia. In recent literature, there has been an increase in SCFN in infants who received whole-body cooling in treatment of neonatal encephalopathy. Subcutaneous fat necrosis is a rare and self-limiting disorder of the adipose tissue that usually occurs in full-term or postterm infants. The disorder can appear days to weeks after birth and spontaneously resolves within weeks to months without any intervention but can have potential complications. With the increasing use of whole-body cooling in the neonate population, clinicians should be aware of SCFN as a possible side effect. This article describes a case of SCFN occurring after whole-body cooling on a term infant with perinatal asphyxia.
Authors:
Amanda G Woods; Carmen K Cederholm
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in neonatal care : official journal of the National Association of Neonatal Nurses     Volume:  12     ISSN:  1536-0911     ISO Abbreviation:  Adv Neonatal Care     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101125644     Medline TA:  Adv Neonatal Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  345-8     Citation Subset:  IM    
Affiliation:
Women's Hospital-Greensboro, North Carolina (Ms Woods); and Alamance Regional Medical Center (Ms Cederholm), Burlington, North Carolina.
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