Document Detail

Subcutaneous adipose tissue metabolism studied by local catheterization.
MedLine Citation:
PMID:  8124394     Owner:  NLM     Status:  MEDLINE    
Adipose tissue is a metabolically active tissue which plays a key role in regulating the concentrations of circulating lipid fuels. In recent years, two new techniques have become available for the study of human adipose tissue metabolism in vivo: microdialysis, and catheterization of the venous drainage from the subcutaneous abdominal adipose tissue. Blood obtained by the latter method shows all the characteristics expected of adipose tissue drainage. The characteristics of this tissue are quite distinct from those of the superficial (mainly skin) or the deep (mainly muscle) tissues of the forearm. The depot studied appears to be typical of adipose tissue as a whole in terms of non-esterified fatty acid release. In comparison with the microdialysis technique, the arterio-venous difference technique allows easier quantification of substrate uptake and release, and allows the study of hydrophobic molecules (e.g. fatty acids, triacylglycerol). On the other hand, it does not allow the study of more than one depot, nor the local introduction of effectors of metabolism (e.g. adrenergic agents). The two techniques are clearly complementary.
K N Frayn; S W Coppack; S M Humphreys
Related Documents :
9688604 - Mitochondrial uncoupling protein may participate in futile cycling of pyruvate and othe...
12062414 - Phytanic acid, but not pristanic acid, mediates the positive effects of phytol derivati...
8338044 - Are dietary saturated, monounsaturated, and polyunsaturated fatty acids deposited to th...
1697464 - The effect of chronic fatty acid treatment on lipolysis in 3t3-l1 adipocytes.
7330224 - Cell growth and the regulation of prostaglandin synthesis.
11703154 - Traceless, self-cleaving solid- and solution-phase parallel synthesis of 3,4,7-trisubst...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity     Volume:  17 Suppl 3     ISSN:  -     ISO Abbreviation:  Int. J. Obes. Relat. Metab. Disord.     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-04-08     Completed Date:  1994-04-08     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  9313169     Medline TA:  Int J Obes Relat Metab Disord     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S18-21; discussion S22     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adipose Tissue / blood supply,  metabolism*
Fatty Acids, Nonesterified / blood,  metabolism
Reg. No./Substance:
0/Fatty Acids, Nonesterified

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Sympathetic activity increases with age. Relationship to blood flow volume and long-term smoking.
Next Document:  Metabolic regulation of sympathetic nervous system activity: lessons from intraneural nerve recordin...