Document Detail


Subcortical profile of memory compromise among HIV-1-infected individuals.
MedLine Citation:
PMID:  19922386     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To examine the hypothesis of subcortical pathologic impairment in HIV/AIDS. METHOD: The study included 22 HIV+, 22 HIV- controls, 22 learning disordered (LD) HIV-, and 22 depressive HIV-. The groups were compared on eight WMS-III Indices. RESULTS: Analyses revealed significantly lower scores (p < .05) in HIV+ on visual immediate memory, immediate memory, visual delayed memory, auditory delayed memory, working memory, and general memory. For all cases, HIV+ participants scored below the control group only. CONCLUSIONS: WMS-III indices discriminated HIV+ participants from normal comparisons. Inability to find differences between HIV+ and depressive and LD groups reflects the isolation of the subcortical effect to the HIV+ group.
Authors:
Allen Schiller; Jessica Foley; William Burns; A L Sellers; Charles Golden
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of neuroscience     Volume:  119     ISSN:  1563-5279     ISO Abbreviation:  Int. J. Neurosci.     Publication Date:  2009  
Date Detail:
Created Date:  2009-11-20     Completed Date:  2010-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0270707     Medline TA:  Int J Neurosci     Country:  England    
Other Details:
Languages:  eng     Pagination:  1779-803     Citation Subset:  IM    
Affiliation:
Harvard Medical School/McLean Hospital, Belmont, Massachusetts, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Depression / complications*,  virology
Female
HIV Infections / complications*
Humans
Intelligence
Learning Disorders / physiopathology,  virology
Male
Memory Disorders / complications*,  diagnosis*,  virology
Middle Aged
Neuropsychological Tests
Psychiatric Status Rating Scales
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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