| Subclinical thyrotoxicosis and the heart. | |
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MedLine Citation:
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PMID: 12165112 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Subclinical thyrotoxicosis is defined as a below normal thyrotropin (TSH) in association with a normal total and free thyroxine (T4) and triiodothyronine (T3). It may be caused by thyroid hormone treatment or by endogenous thyroid disease. The degree of thyrotoxicosis may be estimated by the level of TSH suppression. Subclinical thyrotoxicosis may be associated with changes in cardiac performance and morphology, but this has not been consistently found in all patient populations. Changes may include increased heart rate, increased left ventricular mass index, increased cardiac contractility, diastolic dysfunction, and the induction of ectopic atrial beats or arrhythmias. Cardiac exercise performance may be impaired. Subclinical thyrotoxicosis should be treated in patients with cardiac symptoms or disease. Treatment may include reduction of the thyroid hormone dose, treatment of the underlying thyroid condition, or beta-blockers. |
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Authors:
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Lynn A Burmeister; Angel Flores |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Thyroid : official journal of the American Thyroid Association Volume: 12 ISSN: 1050-7256 ISO Abbreviation: Thyroid Publication Date: 2002 Jun |
Date Detail:
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Created Date: 2002-08-07 Completed Date: 2003-01-31 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9104317 Medline TA: Thyroid Country: United States |
Other Details:
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Languages: eng Pagination: 495-9 Citation Subset: IM |
Affiliation:
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Division of Endocrinology & Metabolism, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. LynnBMD@aol.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cardiomyopathies
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diagnosis,
etiology*,
physiopathology Cardiovascular Physiological Phenomena Exercise Tolerance / drug effects, physiology Hemodynamics / drug effects, physiology Humans Thyrotoxicosis / blood, complications*, therapy Thyrotropin / blood Thyroxine / therapeutic use Ventricular Function, Left / physiology Ventricular Premature Complexes / blood, etiology, physiopathology |
| Chemical | |
Reg. No./Substance:
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7488-70-2/Thyroxine; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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