| Subclinical left ventricular dysfunction in multiple sclerosis. | |
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MedLine Citation:
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PMID: 16867034 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To investigate the left (LV) and right ventricular (RV) function in multiple sclerosis (MS) using standard echocardiography and Doppler tissue imaging (DTI). MATERIALS AND METHODS: A total of 41 patients with definite MS and 32 healthy controls were included in the study. RESULTS: LV end-systolic dimension was increased and LV ejection fraction was decreased in MS patients compared with controls (P < 0.05). LV end-diastolic dimension was increased in MS patients, however, did not reach significance. Among DTI parameters, mitral annular peak early diastolic velocity to peak late diastolic velocity ratio (Em/Am) was decreased in MS patients, but not reach statistical significance. No significant differences in tricuspid annular Em/Am ratio was found between MS patients and controls. A statistically significant increase of DTI derived LV myocardial performance index was found in MS patients as compared with controls. RV myocardial performance index showed a tendency to be increased in MS patients, however, did not reach significance. CONCLUSIONS: These findings suggest subclinical LV dysfunction and preserved RV function in patients with MS. |
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Authors:
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Ferit Akgül; Ismet McLek; Taşkin Duman; Ergün Seyfelì; Tunzale Seydaliyeva; Fatih Yalçin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta neurologica Scandinavica Volume: 114 ISSN: 0001-6314 ISO Abbreviation: Acta Neurol. Scand. Publication Date: 2006 Aug |
Date Detail:
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Created Date: 2006-07-26 Completed Date: 2006-10-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370336 Medline TA: Acta Neurol Scand Country: Denmark |
Other Details:
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Languages: eng Pagination: 114-8 Citation Subset: IM |
Affiliation:
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Mustafa Kemal University, Faculty of Medicine, Department of Cardiology, Antakya, Turkey. feritakgul1@yahoo.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cardiac Output, Low / etiology, physiopathology, ultrasonography Diastole / physiology Echocardiography Female Heart Ventricles / physiopathology*, ultrasonography Humans Male Multiple Sclerosis / complications*, physiopathology* Myocarditis / immunology, physiopathology, ultrasonography Myocardium / immunology* Predictive Value of Tests Systole / physiology Ventricular Dysfunction, Left / etiology*, physiopathology*, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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