Document Detail

Subclinical hypothyroidism presenting with gait abnormality.
MedLine Citation:
PMID:  20220447     Owner:  NLM     Status:  MEDLINE    
Subclinical thyroid disease is a common disorder, particularly in middle-aged and elderly individuals. Some patients with manifest hypothyroidism complain of unsteadiness of gait. The management of subclinical hypothyroidism is controversial. A 61-year-old man presented with a mild gait abnormality. He walked unsteadily on a broad base. Examination revealed a slight cerebellar ataxic gait. Laboratory evaluation showed elevated levels of thyroid-stimulating hormone. Serum free thyroxine was normal and thyroglobulin antibodies were present. Computer tomography of the patient's head was normal, as were other investigations. The patient responded rapidly to thyroxin treatment with resolution of the gait disturbance. A laboratory evaluation of thyroid function should be performed in similar cases, and treatment should be initiated when called for. Subclinical hypothyroidism can present as a cerebellar ataxic gait.
Bengt Edvardsson; Staffan Persson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The neurologist     Volume:  16     ISSN:  2331-2637     ISO Abbreviation:  Neurologist     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-11     Completed Date:  2010-06-14     Revised Date:  2014-11-05    
Medline Journal Info:
Nlm Unique ID:  9503763     Medline TA:  Neurologist     Country:  United States    
Other Details:
Languages:  eng     Pagination:  115-6     Citation Subset:  IM    
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MeSH Terms
Cerebellar Ataxia / diagnosis*
Diagnosis, Differential
Gait Disorders, Neurologic / diagnosis
Head / radiography
Hormones / metabolism,  therapeutic use
Hypothyroidism / diagnosis*,  drug therapy,  metabolism
Middle Aged
Thyroglobulin / immunology
Thyrotropin / metabolism
Thyroxine / metabolism,  therapeutic use
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
0/Hormones; 9002-71-5/Thyrotropin; 9010-34-8/Thyroglobulin; Q51BO43MG4/Thyroxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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