| Subclinical hypothyroidism presenting with gait abnormality. | |
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MedLine Citation:
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PMID: 20220447 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Subclinical thyroid disease is a common disorder, particularly in middle-aged and elderly individuals. Some patients with manifest hypothyroidism complain of unsteadiness of gait. The management of subclinical hypothyroidism is controversial. A 61-year-old man presented with a mild gait abnormality. He walked unsteadily on a broad base. Examination revealed a slight cerebellar ataxic gait. Laboratory evaluation showed elevated levels of thyroid-stimulating hormone. Serum free thyroxine was normal and thyroglobulin antibodies were present. Computer tomography of the patient's head was normal, as were other investigations. The patient responded rapidly to thyroxin treatment with resolution of the gait disturbance. A laboratory evaluation of thyroid function should be performed in similar cases, and treatment should be initiated when called for. Subclinical hypothyroidism can present as a cerebellar ataxic gait. |
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Authors:
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Bengt Edvardsson; Staffan Persson |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The neurologist Volume: 16 ISSN: 1074-7931 ISO Abbreviation: Neurologist Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-11 Completed Date: 2010-06-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9503763 Medline TA: Neurologist Country: United States |
Other Details:
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Languages: eng Pagination: 115-6 Citation Subset: IM |
Affiliation:
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Department of Neurology, Lund University Hospital, S-221 85 Lund, Sweden. Bengt.Edvardsson@med.lu.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebellar Ataxia
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diagnosis* Diagnosis, Differential Gait Disorders, Neurologic / diagnosis Head / radiography Hormones / metabolism, therapeutic use Humans Hypothyroidism / diagnosis*, drug therapy, metabolism Male Middle Aged Thyroglobulin / immunology Thyrotropin / metabolism Thyroxine / metabolism, therapeutic use Tomography, X-Ray Computed Treatment Outcome Walking |
| Chemical | |
Reg. No./Substance:
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0/Hormones; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin; 9010-34-8/Thyroglobulin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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