Document Detail

Subclinical electrophysiological alterations of phrenic nerve in chronic inflammatory demyelinating polyneuropathy.
MedLine Citation:
PMID:  15772737     Owner:  NLM     Status:  MEDLINE    
Alterations of the phrenic nerve (PN) and pulmonary function tests (PFTs) have been described in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). This study was aimed at assessing the relationship between PN and respiratory function in CIDP patients without clinical signs of respiratory failure. Bilateral PN and right median nerve conduction studies were carried out along with blood gas analysis and PFTs: maximal inspiratory pressure; maximal expiratory pressure; forced vital capacity. The amplitude of the compound muscle action potential of the PN was seen to be altered in 19/24 (79%) patients and latency in 22 (92%). Eighteen patients (75%) showed at least one abnormal PFTs or CO2 partial pressure value. Electrophysiological alterations of the PN were observed in a high percentage of the CIDP patients studied. No statistically significant correlation was observed between PN and PFTs alterations.
Dario Cocito; Palma Ciaramitaro; Eugenia Rota; Gianluca Isoardo; Silvana Cannizzo; Fabio Poglio; Alessia Tavella; Lorys Castelli; Ilaria Paolasso; Bruno Bergamasco; Sergio Baldi
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2005-03-21
Journal Detail:
Title:  Journal of neurology     Volume:  252     ISSN:  0340-5354     ISO Abbreviation:  J. Neurol.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-31     Completed Date:  2006-01-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  916-20     Citation Subset:  IM    
U.O. Neurofisiologia Clinica, Dipartimento di Neuroscienze Università di Torino, Via Cherasco 15, 10126 Torino, Italy.
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MeSH Terms
Aged, 80 and over
Electric Stimulation / methods
Electromyography / methods
Evoked Potentials, Motor / physiology,  radiation effects
Functional Laterality
Middle Aged
Neural Conduction / physiology*
Phrenic Nerve / physiopathology*
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / physiopathology*
Reaction Time / physiology,  radiation effects
Respiratory Function Tests / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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