Document Detail

Subclinical autonomic dysfunction in patients with beta-thalassemia.
MedLine Citation:
PMID:  22170296     Owner:  NLM     Status:  Publisher    
We electrophysiologically evaluated the autonomic function (AF) in a consecutive series of patients with beta-thalassemia and in normal individuals. Six quantitative autonomic function tests (AFTs) were used: tilt test, hand grip test and sympathetic skin response for sympathetic function; R-R interval, inspiration-expiration difference and 30/15 ratio for parasympathetic function. The prevalence of impaired AF was higher in beta-thalassemia patients (13%, n = 5) than in control subjects (0%, n = 0; p = 0.026). Subclinical autonomic dysfunction appeared to be more prevalent in beta-thalassemia patients compared to controls in our series. Further independent validation of this finding is required in larger cohorts of beta-thalassemia patients.
Elefterios Stamboulis; Nikoleta Vlachou; Konstantinos Voumvourakis; Athina Andrikopoulou; Chrisa Arvaniti; Athanasios Tsivgoulis; Dimitrios Athanasiadis; Sotirios Tsiodras; Nikolaos Tentolouris; Heleni Triantafyllidi; Marouso Drossou-Servou; Aphrodite Loutradi-Anagnostou; Georgios Tsivgoulis
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-15
Journal Detail:
Title:  Clinical autonomic research : official journal of the Clinical Autonomic Research Society     Volume:  -     ISSN:  1619-1560     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9106549     Medline TA:  Clin Auton Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Second Department of Neurology, Attikon Hospital, University of Athens, Iras 39, 15344, Athens, Greece.
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