Document Detail

Subclinical atherosclerosis in gouty arthritis patients: a comparative study.
MedLine Citation:
PMID:  21442166     Owner:  NLM     Status:  Publisher    
We evaluated the incidence of subclinical atherosclerosis and associated factors in our gouty arthritis patients. We included 55 gouty arthritis patients diagnosed at our center within the last 4 years. The control group included 41 patients with rheumatoid arthritis (RA) and 34 patients with asymptomatic hyperuricemia (AHU). Atherosclerotic risk factors were determined in all subjects. Carotid intima-media thickness (IMT) and the presence of plaques were evaluated by B-mode ultrasonography. The carotid IMT in gouty arthritis patients (0.730 ± 0.19) was significantly higher than in AHU subjects (0.616 ± 0.12) (P = 0.004) and tended to be higher than the RA group (0.669 ± 0.17) (P = 0.1). Atheromatous plaques were significantly more frequent in gouty arthritis patients (16 cases, 29.1%) than in RA patients (5 cases, 12.2%) and AHU subjects (3 cases, 8.8%) (P values, 0.05 and 0.023). Gout patients with plaques were older (P = 0.006) and tended to have tophi more frequently (P = 0.06). Logistic regression analysis showed that age (OR: 1.3, 95% CI: 1.02-1.54) and the presence of tophi (OR: 12.5, 95% CI: 1.2-140) were independent risk factors for the presence of plaques. Gouty arthritis bears a higher risk of atherosclerosis than both RA and AHU.
Selçuk Cukurova; Omer Nuri Pamuk; Ercüment Unlü; Gülsüm Emel Pamuk; Necati Cakir
Related Documents :
21846296 - Maxillary sinus infundibulum narrowing influences sinus abnormalities in spite of the p...
8323396 - Baseline plasma fibrinolysis and its correlation with clinical manifestations in patien...
22349136 - Serum il-33 but not st2 level is elevated in intermittent allergic rhinitis and is a ma...
603216 - Coagulation disorders in severely and critically injured patients.
21968236 - Characteristics of vascular involvement in behçet's disease in japan: a retrospective ...
12363386 - Decreased calcium-dependent constitutive nitric oxide synthase (cnos) activity in prefr...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-27
Journal Detail:
Title:  Rheumatology international     Volume:  -     ISSN:  1437-160X     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Internal Medicine, Trakya University Medical Faculty, Edirne, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Relationship between arterial dysfunction and extra-articular features in patients with rheumatoid a...
Next Document:  Characteristics and influence factors of pathologic transformation in the subclasses of class IV lup...