Document Detail


Subclinical hypothyroidism after vascular complicated pregnancy.
MedLine Citation:
PMID:  23323892     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Women with a history of vascular complicated pregnancy are at risk for developing remote cardiovascular disease. It is associated with underlying cardiovascular risk factors both jeopardizing trophoblast and vascular function. Subclinical hypothyroidism may relate to both conditions.
METHODS: In 372 women with a history of vascular complicated pregnancy, we assessed thyroid function.
RESULTS: Subclinical hypothyroidism was diagnosed in 73/372 women (19.6%). It occurred more often when pregnancy ended before 32 weeks of gestation (p = 0.008).
CONCLUSION: In this cohort, subclinical hypothyroidism is more common after very preterm delivery. It may contribute to the elevated risk of remote cardiovascular disease.
Authors:
Moniek van der Zanden; Rianne J Hop-de Groot; Fred C G J Sweep; H Alec Ross; Martin den Heijer; Marc E A Spaanderman
Publication Detail:
Type:  Journal Article     Date:  2013-01-16
Journal Detail:
Title:  Hypertension in pregnancy     Volume:  32     ISSN:  1525-6065     ISO Abbreviation:  Hypertens Pregnancy     Publication Date:  2013  
Date Detail:
Created Date:  2013-02-11     Completed Date:  2014-04-22     Revised Date:  2014-07-23    
Medline Journal Info:
Nlm Unique ID:  9421297     Medline TA:  Hypertens Pregnancy     Country:  England    
Other Details:
Languages:  eng     Pagination:  1-10     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abruptio Placentae / blood,  epidemiology
Adult
Female
Fetal Growth Retardation / blood,  epidemiology*
Humans
Hypertension, Pregnancy-Induced / blood,  epidemiology*
Hypothyroidism / blood,  epidemiology*,  etiology
Lipids / blood
Netherlands / epidemiology
Pregnancy
Prevalence
Thyroid Function Tests
Chemical
Reg. No./Substance:
0/Lipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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