Document Detail

Subcellular distribution of trace elements in the liver of sea turtles.
MedLine Citation:
PMID:  12398389     Owner:  NLM     Status:  MEDLINE    
Subcellular distribution of Cu, Zn, Se, Rb, Mo, Ag, Cd and Pb was determined in the liver of green turtles (Chelonia mydas) and hawksbill turtles (Eretmochelys imbricata) from Yaeyama Islands, Japan. Also, hepatic cytosol from sea turtles was applied on a Sephadex G-75 column and elution profiles of trace elements were examined. Copper, Zn, Se, Rb, Ag and Cd were largely present in cytosol in the liver of both species, indicating that cytosol was the significant site for the accumulation of these elements in sea turtles. In contrast, Mo and Pb were accumulated specifically in nuclear and mitochondrial fraction and microsomal fraction, respectively. Gel filtration analysis showed that Cu, Zn, Ag and Cd were bound to metallothionein (MT) in the cytosol of sea turtles. To our knowledge, this is the first report on the association of trace elements with MT in sea turtles.
Yasumi Anan; Takashi Kunito; Haruya Sakai; Shinsuke Tanabe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Marine pollution bulletin     Volume:  45     ISSN:  0025-326X     ISO Abbreviation:  Mar. Pollut. Bull.     Publication Date:  2002  
Date Detail:
Created Date:  2002-10-25     Completed Date:  2003-02-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0260231     Medline TA:  Mar Pollut Bull     Country:  England    
Other Details:
Languages:  eng     Pagination:  224-9     Citation Subset:  IM    
Center for Marine Environmental Studies, Ehime University, Matsuyama, Japan.
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MeSH Terms
Cytosol / chemistry
Environmental Exposure
Liver / chemistry*,  cytology
Mitochondria / chemistry
Trace Elements / pharmacokinetics*
Reg. No./Substance:
0/Trace Elements

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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