| Subarachnoid Hemorrhage and Intracerebral Hematoma due to Sildenafil Ingestion in a Young Adult. | |
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MedLine Citation:
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PMID: 20379474 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Sildenafil citrate (Viagra(R); Pfeizer US Pharmaceutical Group, New York, NY, USA) is a potent vasodilating agent to treat male erectile dysfunction. Among its adverse effects, hemorrhagic stroke has not been widely reported yet. We present a case of a 33-year-old healthy man who ingested 50 mg sildenafil a half hour before onset of headache, nervousness and speech disturbance. Head computed tomogram of this stuporous man showed huge intracerebral hemorrhage and thick subarachnoid hemorrhage, but angiography failed to disclose any vascular anomalies. Subsequent surgical procedure was followed, and rehabilitation was provided thereafter. Sildenafil seems to act by redistributing arterial blood flow, and concurrent sympathetic hyperactivity, which lead to such hemorrhagic presentation. Extreme caution should be paid on even in a young adult male patient wven without known risk factors. |
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Authors:
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Hyoung-Soo Byoun; Young-Joon Lee; Hyeong-Joong Yi |
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Publication Detail:
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Type: Journal Article Date: 2010-03-31 |
Journal Detail:
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Title: Journal of Korean Neurosurgical Society Volume: 47 ISSN: 1598-7876 ISO Abbreviation: J Korean Neurosurg Soc Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-04-09 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101467054 Medline TA: J Korean Neurosurg Soc Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 210-2 Citation Subset: - |
Affiliation:
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Department of Neurosurgery, Hanyang University Medical Center, Seoul, Korea. |
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