Document Detail

Subacute thyroiditis in an immunosuppressed patient.
MedLine Citation:
PMID:  11929089     Owner:  NLM     Status:  MEDLINE    
Subacute thyroiditis is a well-recognized cause of transient thyrotoxicosis, resulting from a destruction injury to the thyroid. The pathogenesis of this condition is not completely understood and there is debate regarding the extent of the contribution of autoimmunity and external agents, such as infections, to this process. We present the first reported case of subacute thyroiditis in a patient who had been on chronic lithium therapy as well as long-term immunosuppression, with cyclosporin and prednisolone, following an allogeneic bone marrow transplant. We speculate that this case suggests a minimal role of autoimmunity in the development of subacute thyroiditis.
K Obuobie; A Al-Sabah; J H Lazarus
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  25     ISSN:  0391-4097     ISO Abbreviation:  J. Endocrinol. Invest.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-04-03     Completed Date:  2002-09-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  169-71     Citation Subset:  IM    
Department of Medicine, University Hospital of Wales, Cardiff, UK.
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MeSH Terms
Bone Marrow Transplantation
Cyclosporine / administration & dosage,  adverse effects
Immunosuppression / adverse effects*
Immunosuppressive Agents / administration & dosage,  adverse effects
Lithium / administration & dosage
Prednisolone / administration & dosage,  therapeutic use
Propranolol / administration & dosage
Thyroiditis, Subacute / immunology*
Thyrotropin / blood
Thyroxine / blood
Reg. No./Substance:
0/Immunosuppressive Agents; 50-24-8/Prednisolone; 525-66-6/Propranolol; 59865-13-3/Cyclosporine; 7439-93-2/Lithium; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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