Document Detail

Subacute sclerosing panencephalitis: is there something different in the younger children?
MedLine Citation:
PMID:  16829007     Owner:  NLM     Status:  MEDLINE    
Subacute sclerosing panencephalitis is a rare, slow viral infection caused by a defective measles virus. Although it is a rare disease, it is still important in developing countries. The onset is generally between the ages of 5-15 years. We reported the clinical and laboratory profile and nature of 9 patients under the age of 4 years with SSPE. Although it is known that a few patients with SSPE have an acute and rapidly fulminating course, in this study rate of progression was rapidly progressive in 6 patients and progressive in 3 of them on admission. Unfortunately, 4 of them were lost to follow up because of address and/or telephone number alterations. Although the number of patients in this study is not sufficient, we suggest that SSPE patients under the age of 4 years have a poor prognosis as a result of progressive or rapidly progressive course despite medical treatment.
Deniz Yilmaz; Omer Faruk Aydin; Nesrin Senbil; Deniz Yuksel
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2006-07-07
Journal Detail:
Title:  Brain & development     Volume:  28     ISSN:  0387-7604     ISO Abbreviation:  Brain Dev.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-09     Completed Date:  2006-12-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909235     Medline TA:  Brain Dev     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  649-52     Citation Subset:  IM    
Dr. Sami Ulus Children's Hospital, Department of Pediatric Neurology, Ankara, Turkey.
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MeSH Terms
Child, Preschool
Immunoglobulin G / cerebrospinal fluid
Measles virus / immunology,  isolation & purification
Retrospective Studies
Subacute Sclerosing Panencephalitis* / epidemiology,  pathology,  physiopathology
Reg. No./Substance:
0/Immunoglobulin G

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