Document Detail

Subacute sclerosing panencephalitis: a cause of acute vision loss.
MedLine Citation:
PMID:  15351023     Owner:  NLM     Status:  MEDLINE    
A 4-year-old male presented with only acute vision loss. His neurologic examination, funduscopic examination, and pupils were normal. Cranial magnetic resonance imaging revealed abnormal hyperintense, bilaterally symmetric lesions (on T(2)-weighted and fluid-attenuated inversion recovery, images) in bilateral optic radiations, pulvinar region in the thalami, crus posterior of internal capsules, periventricular white matter, and unilaterally left anterior pons. Elevated measles antibody titers in the cerebrospinal fluid confirmed the diagnosis of subacute sclerosing panencephalitis. Vision loss improved and cranial magnetic resonance imaging findings regressed,but myoclonic jerks and deterioration began 7 months later. The diagnosis of subacute sclerosing panencephalitis should be considered in cases with acute vision loss resulting from cortical blindness even when classical findings of the central nervous system do not exist.
Nesrin Senbil; O Faruk Aydin; Hülya Orer; Y K Yavuz Gürer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurology     Volume:  31     ISSN:  0887-8994     ISO Abbreviation:  Pediatr. Neurol.     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-07     Completed Date:  2004-12-13     Revised Date:  2006-05-23    
Medline Journal Info:
Nlm Unique ID:  8508183     Medline TA:  Pediatr Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  214-7     Citation Subset:  IM    
Department of Pediatric Neurology, Dr. Sami Ulus Children's Hospital, Ankara, Turkey.
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MeSH Terms
Acute Disease
Blindness, Cortical / diagnosis,  etiology*
Child, Preschool
Subacute Sclerosing Panencephalitis / complications*,  diagnosis

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