| Sub-optimal function of the auditory brainstem in term infants with transient low Apgar scores. | |
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MedLine Citation:
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PMID: 17368093 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To assess functional integrity of the auditory brainstem in neonates with transient low Apgar scores. METHODS: Forty-two term infants were studied with brainstem auditory evoked response (BAER) using the maximum length sequence during the first month of life. All had transient low Apgar scores but no clinical signs of hypoxic-ischaemic encephalopathy (HIE). RESULTS: The latencies of BAER waves I and III in these infants were similar to those of age-matched normal controls at all click rates (91/s, 227/s, 455/s and 910/s) during the period studied. Wave V latency was increased at 910/s on day 1 (P<0.01), but did not differ from that in the controls on any other days. I-V interval was increased significantly at 455/s and 910/s on day 1 (P<0.01 and 0.001) and day 3 (P<0.05 and 0.01). On days 5 and 7, BAER wave latencies and intervals were similar to those in the controls. On day 30, all latencies and intervals reached the values in the controls. No abnormalities were seen in BAER wave amplitude variables on any days. CONCLUSIONS: Neonates with transient low Apgar scores but without HIE had a significant increase in I-V interval at very high click rates on the first three days of life. SIGNIFICANCE: Brainstem auditory function is sub-optimal during the first few days in neonates with transient low Apgar scores. |
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Authors:
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Ze D Jiang; Xu Xiu; Dorothea M Brosi; Xiao M Shao; Andrew R Wilkinson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-03-23 |
Journal Detail:
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Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: 118 ISSN: 1388-2457 ISO Abbreviation: Clin Neurophysiol Publication Date: 2007 May |
Date Detail:
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Created Date: 2007-04-09 Completed Date: 2007-06-11 Revised Date: 2008-09-10 |
Medline Journal Info:
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Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1088-96 Citation Subset: IM |
Affiliation:
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Children's Hospital, Fudan University, Shanghai, China. zedong.jiang@paediatrics.ox.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acoustic Stimulation Aging / physiology Apgar Score* Data Interpretation, Statistical Electroencephalography Evoked Potentials, Auditory, Brain Stem / physiology* Female Humans Hypoxia, Brain / physiopathology Infant, Newborn Male Pregnancy Pregnancy Outcome |
| Grant Support | |
ID/Acronym/Agency:
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//Wellcome Trust |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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