Document Detail


Stuttering acquired from subcortical pathologies and its alleviation from thalamic perturbation.
MedLine Citation:
PMID:  1611465     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acquired stuttering subsequent to subcortical pathology of mesothalamus was observed in four neurosurgical subjects. The patients suffered from chronic pain, seizures, and somatosensory disorders. They also exhibited unpredictable and uncontrollable speech, spasmodic blocks which were devoid of accessory features, and adaptation effect. Therapeutic mesothalamic stimulation, used as a treatment of last resort to relieve the pain and associated symptoms, also had an ameliorating effect on the stuttering. Spontaneously occurring focal abnormal EEG discharges were anatomically delineated and used as a guide for therapeutic stimulation electrode placement. Attentuation of the abnormal discharges was followed by alleviation of symptoms. This investigation examines the clinical characteristics of stuttering in four neurosurgical patients and suggests an electropathologic basis for their mesothalamic-generated speech dysfluencies. The cooccurrence of pain, seizures, somatosensory disorders, and stuttering, and their concurrent amelioration, suggests that both chronic pain and stuttering may be implicated by similar or related reticular electropathologic generators, couched in overlapping reticular networks extending from the brain stem to the thalamus, and that the acquired stuttering may be recruited as one component of a larger syndrome complex.
Authors:
O J Andy; S C Bhatnagar
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Brain and language     Volume:  42     ISSN:  0093-934X     ISO Abbreviation:  Brain Lang     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-07-29     Completed Date:  1992-07-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7506220     Medline TA:  Brain Lang     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  385-401     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, University of Mississippi Medical Center.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Brain Mapping
Electric Stimulation Therapy / instrumentation*
Electrodes, Implanted
Female
Humans
Male
Middle Aged
Movement Disorders / physiopathology,  therapy
Pain, Intractable / physiopathology,  therapy
Seizures / physiopathology,  therapy
Stereotaxic Techniques
Stuttering / physiopathology*,  therapy
Thalamic Nuclei / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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