| Sturge-Weber syndrome and dermatomal facial port-wine stains: incidence, association with glaucoma, and pulsed tunable dye laser treatment effectiveness. | |
| | |
MedLine Citation:
|
PMID: 18349634 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Laser therapy is the optimal approach for treating port-wine stains, but whether it is effective for patients with facial dermatomal port-wine stains and Sturge-Weber syndrome is undetermined. This project aimed to verify the incidence of Sturge-Weber syndrome and glaucoma within the population, compare the response in syndromic and nonsyndromic patients with facial dermatomal port-wine stains to laser, and determine the treatment response in relation to dermatome and color. METHODS: The authors retrospectively reviewed 874 patients with facial port-wine stains (203 displayed a dermatomal pattern). Pretreatment and posttreatment photographs were assessed clinically and recorded on a statistically reliable percentage gradient. RESULTS: Sturge-Weber syndrome was diagnosed in 30 patients. Twelve patients had glaucoma, with the port-wine stains involving the ophthalmic (V1) division of the trigeminal nerve. The highest proportion of patients with glaucoma came from those with involvement of the maxillary (V2) and/or mandibular (V3) division of the trigeminal nerve. No patients had Sturge-Weber syndrome with V3 port-wine stains alone. After laser therapy, only 45 percent of syndromal patients and 55 percent of nonsyndromic patients had a satisfactory outcome (>50 percent) in color and size reduction of dermatomal port-wine stains. CONCLUSIONS: The incidence of Sturge-Weber syndrome was 3 percent in patients with a facial port-wine stain. There was an increased risk of Sturge-Weber syndrome with involvement of V1 port-wine stains and no risk with involvement of V3 port-wine stains alone. Laser treatment produced unsatisfactory outcomes in patients with facial dermatomal port-wine stains. V3 port-wine stains responded best and V2 worst to laser. |
| | |
Authors:
|
Anusha A Hennedige; Awf A Quaba; Khalil Al-Nakib |
Related Documents
:
|
10325854 - Epidural analgesia in an obstetric patient with klippel-trenaunay syndrome. 14673584 - Multiple vascular abnormalities and a paradoxical combination of vitamin b12 deficiency... 8990604 - Sunct syndrome. statuslike pattern. 6606364 - Klippel-feil syndrome and associated ear deformities. 7535294 - Hepatitis c virus and sjögren's syndrome. 19055414 - Effect of functionalization of multiwalled nanotubes on the crystallization and hydroly... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Plastic and reconstructive surgery Volume: 121 ISSN: 1529-4242 ISO Abbreviation: Plast. Reconstr. Surg. Publication Date: 2008 Apr |
Date Detail:
|
Created Date: 2008-03-19 Completed Date: 2008-04-29 Revised Date: 2011-02-16 |
Medline Journal Info:
|
Nlm Unique ID: 1306050 Medline TA: Plast Reconstr Surg Country: United States |
Other Details:
|
Languages: eng Pagination: 1173-80 Citation Subset: AIM; IM |
Affiliation:
|
St. John's Hospital, Livingston, West Lothian, Scotland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Child Child, Preschool Female Glaucoma / complications* Humans Incidence Infant Lasers, Dye* Male Middle Aged Port-Wine Stain / complications*, epidemiology, radiotherapy*, surgery* Retrospective Studies Sturge-Weber Syndrome / complications*, epidemiology, radiotherapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: High-dose ultraviolet light exposure reduces scar hypertrophy in a rabbit ear model.
Next Document: Anthropometric analysis of levator muscle function.