Document Detail

Studying the expansion of small abdominal aortic aneurysms: is there a role for peak wall stress?
MedLine Citation:
PMID:  21804486     Owner:  NLM     Status:  In-Data-Review    
AIM: The aim of this paper was to study the characteristics of three distending small abdominal aortic aneurysms (AAAs), with an increase in maximal diameter from 5 to 5.5 cm or above.
METHODS: Peak Wall Stress (PWS) in the presence and absence of intraluminal thrombus (ILT) was evaluated in 3 cases of small AAAs (5 cm), at initial presentation and after their expansion, at maximum diameters ≥5.5 cm using finite element analysis. Furthermore, AAA sac volume (Vsac), the percentage volume of ILT (ILT%) and the percentage change of Vsac (ΔV%) and ILT (ILT%) were estimated and the location of PWS was recorded.
RESULTS: Two AAA expanded from 5cm to 5.5 cm in a period of 6 months after initial presentation, with increase of sac volume by 20% and 30%, respectively. The third AAA expanded to a diameter of 6.5 cm after a follow-up period of 13 months, with a subsequent increase in sac volume of 78%. The expansion of AAA max diameter did not correlate with differences in peak wall stress (PWS) values at the initial presentation, ranging from 20.5 to 21.3 Nt/cm2.
CONCLUSION: PWS values cannot solely serve as a predictive tool for small AAA expansion. Small AAA expansion seem to be a multifactorial process, not solely described by PWS values but rather by a combination of mechanical, hemodynamic and biological factors.
E Georgakarakos; C Ioannou; Y Papaharilaou; T Kostas; G Kozyrakis; A Katsamouris
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  30     ISSN:  1827-1839     ISO Abbreviation:  Int Angiol     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-08-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  462-6     Citation Subset:  IM    
Department of Vascular Surgery, University of Crete Medical School, Heraklion, Greece2 Institute of Applied and Computational Mathematics, Foundation for Research and Technology-Hellas, Heraklion, Greece -
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