| Study of testicular feedback in male rats using artificial cryptorchidism as a model. | |
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MedLine Citation:
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PMID: 38197 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Plasma LH, FSH and testosterone were measured in testosterone-treated and untreated cryptorchid and castrated male rats. Exogenous testosterone prevented the increase in basal LH but not FSH levels seen in the untreated cryptorchids. Increases in plasma LH and FSH in response to LH-RH were greater in the cryptorchid as compared to the control group and this could not be reversed by exogenous testosterone, suggesting that spermatogenesis-related feedback factors regulate LH as well as FSH at the pituitary level in the intact rat. The results were consistent with a reduced but nevertheless significant secretion of inhibin by the cryptorchid testis. Basal plasma testosterone levels and ventral prostate weights were not significantly different from intact animals. |
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Authors:
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C R Hopkinson; S Chari; G Sturm; C Hirschhäuser |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Hormone research Volume: 10 ISSN: 0301-0163 ISO Abbreviation: Horm. Res. Publication Date: 1979 |
Date Detail:
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Created Date: 1979-10-24 Completed Date: 1979-10-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0366126 Medline TA: Horm Res Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 310-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Androgens
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blood Animals Castration Cryptorchidism / metabolism, physiopathology* Disease Models, Animal Feedback Follicle Stimulating Hormone / blood Gonadotropin-Releasing Hormone / pharmacology Luteinizing Hormone / blood Male Pituitary Gland / metabolism, physiology* Prostate / physiology Rats Testis / metabolism, physiology* Testosterone / blood, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Androgens; 33515-09-2/Gonadotropin-Releasing Hormone; 58-22-0/Testosterone; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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