Document Detail

Study on risk factors of cryptorchidism
MedLine Citation:
PMID:  12411087     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Cryptorchidism is the most common urogenital congenital malformations in males, which increases male infertility and testicular tumors. It is necessary to identify its risk factors. METHODS: A hospital-based case-control study was conducted. Cases were 99 boys with cryptorchidism with two matched controls per case were randomly selected. Both cases and controls were interviewed with a uniformed questionnaire by face to face. Conditional logistic regression model was used for univariable and multivariate analysis by SAS6.12 computer software was used to estimate odds ratios (OR) and their 95 per cent confidence internals (95% CI). RESULTS: Multiple conditional logistic regression analysis showed that cryptorchidism was positively associated with maternal common cold accompanied fever in the first trimester (OR = 9.37, 95% CI: 2.25 - 39.09), with threatened abortion in the first and/or second trimester (OR = 4.66, 95% CI: 2.02 - 10.74), maternal preeclampsia during pregnancy (OR = 16.33, 95% CI: 1.40 - 191.20), paternal exposure to pesticides occupationally (OR = 12.79, 95% CI: 2.90 - 56.43), neonatal low birth weight (OR = 5.77, 95% CI: 1.39 - 23.98), and maternal age under 24 years (OR = 2.89, 95% CI: 1.29 - 4.06). CONCLUSIONS: The risk factors of cryptorchidism were maternal common cold accompanied fever in the first trimester, threatened abortion in the first and/or second trimester, maternal preeclampsia during pregnancy, paternal exposure to pesticides occupationally, neonatal low birth weight, maternal age under 24 years.
Jinping Wang; Binyou Wang
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Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi     Volume:  23     ISSN:  0254-6450     ISO Abbreviation:  Zhonghua Liu Xing Bing Xue Za Zhi     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-11-04     Completed Date:  2002-12-04     Revised Date:  2009-12-29    
Medline Journal Info:
Nlm Unique ID:  8208604     Medline TA:  Zhonghua Liu Xing Bing Xue Za Zhi     Country:  China    
Other Details:
Languages:  chi     Pagination:  190-3     Citation Subset:  IM    
Department of Cardiovescular Disease, Oilfields General Hospital in Daqing, Daqing 163001, China.
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MeSH Terms
Case-Control Studies
Child, Preschool
Cryptorchidism / etiology*
Logistic Models
Maternal Age
Occupational Exposure / adverse effects
Paternal Exposure / adverse effects
Pesticides / adverse effects
Pregnancy Complications
Prenatal Exposure Delayed Effects
Risk Factors
Reg. No./Substance:

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