Document Detail


Study of photoablation of rabbit corneas by Er:YAG laser.
MedLine Citation:
PMID:  8836994     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND OBJECTIVE: This work studied the ablation mechanisms of rabbit corneas by the Erbium:YAG laser. The occurrence of thermal and mechanical damages in the tissue as a function of the laser fluence was also investigated. STUDY DESIGN/MATERIALS AND METHODS: The experiments were performed both on enucleated eyes and in vivo. An ultrafast imaging technique was used to investigate the dynamic evolution of the ablation. The treated samples underwent histological and ultrastructural study. RESULTS: A single high fluence laser shot led to the complete removal of the epithelium by a photomechanical effect. In eyes whose epithelium was manually removed, high fluence pulses resulted in evident tears in the stroma, whereas low fluence pulses led to few microns deep incisions, characterized by limited mechanical and thermal damages. CONCLUSION: The photomechanical action plays a significant role in the ablation of the cornea by Erbium laser. Precise control of the fluence is required to avoid cracking phenomena in the stroma.
Authors:
R Cubeddu; R Brancato; C Sozzi; P Taroni; G Trabucchi; G Valentini; M Verdi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Lasers in surgery and medicine     Volume:  19     ISSN:  0196-8092     ISO Abbreviation:  Lasers Surg Med     Publication Date:  1996  
Date Detail:
Created Date:  1996-12-17     Completed Date:  1996-12-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8007168     Medline TA:  Lasers Surg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  32-9     Citation Subset:  IM    
Affiliation:
C.E.Q.S.E.-C.N.R., Politecnico di Milano, Italy.
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MeSH Terms
Descriptor/Qualifier:
Aluminum Silicates
Animals
Cornea / anatomy & histology,  cytology,  surgery*,  ultrastructure
Corneal Stroma / injuries,  surgery
Cytoplasm / ultrastructure
Epithelial Cells
Epithelium / surgery,  ultrastructure
Erbium
Hot Temperature
Image Processing, Computer-Assisted / instrumentation
Laser Therapy* / instrumentation,  methods
Lasers*
Rabbits
Vacuoles / ultrastructure
Video Recording / instrumentation
Yttrium
Chemical
Reg. No./Substance:
0/Aluminum Silicates; 7440-52-0/Erbium; 7440-65-5/Yttrium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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