Document Detail


Study of perfusion in and around cerebral contusions by means of computed tomography.
MedLine Citation:
PMID:  19388326     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Several authors have found low absolute values of cerebral blood flow (CBF) in both contusion core and pericontusional parenchyma ofhead-injured patients by means of Xenon Computed Tomography (CT). Perfusion CT has become available as a new and validated tool for studying CBF in patients. The aim of the present study was to assess the relation between volume expansion of contusions and pericontusional CBF measured by perfusion CT. METHODS: Eight head-injured patients with a contusion on the admission CT head scan underwent a perfusion CT scan within 48 hours post trauma. The patients received standard head injury management. The eventual maximum contusion volume was assessed on the follow up plain CT scans. FINDINGS: Expansion of the contusion was observed in 6 patients. Reduced CBF was found in all contusions with absolute CBF values below 10 ml/100 g/min in the CT hyperdense/mixed density areas and below 20 ml/100 g/min in the surrounding hypodense areas. Penumbra areas, when defined by a mean transit time > 150% and cerebral blood volume > 2 ml/100 g, were limited to thin concentric rims surrounding the ischemic cores. We could not find a pattern of CBF that predicted contusion expansion. CONCLUSIONS: Based on the present preliminary data there is no indication that contusion expansion can be predicted on the basis of pericontusional CBF data.
Authors:
Bart Depreitere; Richard Aviv; Sean Symons; Michael Schwartz; Walter Coudyzer; Guy Wilms; Guy Marchal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurochirurgica. Supplement     Volume:  102     ISSN:  0065-1419     ISO Abbreviation:  Acta Neurochir. Suppl.     Publication Date:  2008  
Date Detail:
Created Date:  2009-04-24     Completed Date:  2009-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100962752     Medline TA:  Acta Neurochir Suppl     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  259-62     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium. bart.depreitere@uzleuven.be
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Blood Flow Velocity / physiology
Cerebral Cortex / radiography*
Cerebrovascular Circulation / physiology
Craniocerebral Trauma / pathology*
Female
Follow-Up Studies
Humans
Male
Middle Aged
Perfusion / methods
Radiographic Image Interpretation, Computer-Assisted / methods
Regional Blood Flow / physiology
Retrospective Studies
Tomography, X-Ray Computed / methods*

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