Document Detail

Study on the organoleptic intensity scale for measuring oral malodor.
MedLine Citation:
PMID:  14691119     Owner:  NLM     Status:  MEDLINE    
The 0-5 organoleptic scale is used widely in breath research and in trials to measure the efficacy of anti-odor agents. However, the precise relationship between odor scores and gas concentrations of target odorants is unknown. The purpose of this study was to relate mean organoleptic scores from odor judges (n = 7) for pure odorants (n = 8) representative of those found in oral malodor. Judges used a common 0-5 scale to report the odor intensity of sample sets in random order of concentration. Regression analysis of data showed that odor score was proportional to the log concentration of odorant, and comparison of slopes showed H(2)S to be the most significant in terms of odor power. Detection thresholds ( were: Skatole (7.2 x 10(-13)) < methylmercaptan (1.0 x 10(-11)) < trimethylamine (1.8 x 10(-11)) < isovalerate (1.8 x 10(-11)) < butyrate (2.3 x 10(-10)) < hydrogen sulphide (6.4 x 10(-10)) < putrescine (9.1 x 10(-10)) < dimethyl disulphide (5.9 x 10(-8)). The study demonstrates the exponential nature of the olfactory response and shows that any single compound's contribution to malodor depends on odor power and threshold in addition to concentration.
J Greenman; J Duffield; P Spencer; M Rosenberg; D Corry; S Saad; P Lenton; G Majerus; S Nachnani; M El-Maaytah
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of dental research     Volume:  83     ISSN:  0022-0345     ISO Abbreviation:  J. Dent. Res.     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2003-12-23     Completed Date:  2004-03-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0354343     Medline TA:  J Dent Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  81-5     Citation Subset:  D; IM    
Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Coldharbour Lane, Bristol, BS16 1QY, UK.
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MeSH Terms
Butyrates / analysis
Disulfides / analysis
Halitosis / diagnosis*
Hydrogen Sulfide / analysis
Linear Models
Methylamines / analysis
Odors* / analysis
Pentanoic Acids / analysis
Putrescine / analysis
Sensory Thresholds / physiology
Skatole / analysis
Smell / physiology
Sulfhydryl Compounds / analysis
Reg. No./Substance:
0/Butyrates; 0/Disulfides; 0/Methylamines; 0/Pentanoic Acids; 0/Sulfhydryl Compounds; 110-60-1/Putrescine; 503-74-2/isovaleric acid; 624-92-0/dimethyl disulfide; 74-93-1/methylmercaptan; 75-50-3/trimethylamine; 7783-06-4/Hydrogen Sulfide; 83-34-1/Skatole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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