Document Detail


Study of the neurobehavioural toxicity of styrene at low levels of exposure.
MedLine Citation:
PMID:  8482595     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Thirty workers in a dockyard exposed to concentrations of styrene lower than the TLV-TWA of 50 ppm and 30 control workers not subject to exposure but employed by the same company were subjected to three psychometric tests on one Monday morning and evening. The results were usually better in the evening than in the morning in both groups, which proves the lack of acute intoxication at the end of the day at this level of exposure. On the other hand, all of the tests conducted on the exposed subjects are significantly less good than those on the controls. The results suggest the existence of minor but significant organic mental disorders in the subjects exposed to a mean dose of 30 ppm in this study. These results are inconsistent with those of several recent studies. The advisability of lowering the TLV of 50 ppm in discussed.
Authors:
D Jégaden; D Amann; J F Simon; M Habault; B Legoux; P Galopin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International archives of occupational and environmental health     Volume:  64     ISSN:  0340-0131     ISO Abbreviation:  Int Arch Occup Environ Health     Publication Date:  1993  
Date Detail:
Created Date:  1993-06-01     Completed Date:  1993-06-01     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7512134     Medline TA:  Int Arch Occup Environ Health     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  527-31     Citation Subset:  IM    
Affiliation:
Service de Médecine du Travail, DCN Lorient, Délégation Générale pour l'Armement, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / drug effects
Case-Control Studies
Female
Humans
Male
Memory Disorders / chemically induced*
Occupational Diseases / chemically induced*
Occupational Exposure / adverse effects*,  analysis
Perceptual Disorders / chemically induced*
Psychometrics
Styrene
Styrenes / adverse effects*,  analysis
Vision, Ocular / drug effects
Chemical
Reg. No./Substance:
0/Styrenes; 100-42-5/Styrene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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