| Study of mycotoxin calibration approaches on the example of trichothecenes analysis from flour. | |
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MedLine Citation:
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PMID: 22465005 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The aim of this study was to evaluate the applicability of different calibration approaches in a trichothecenes analysis for wheat flour. Concretely eight trichothecenes (five type B trichothecenes and three type A trichothecenes) were analyzed by matrix solid-phase dispersion (MSPD) and liquid chromatography-tandem mass spectrometry (LC-MS/MS). In the first set of experiments the presence of matrix effects was evaluated; values ranged between 59% and 79%. In the second set of experiments, solutions to compensate these signal suppressions were examined. Different calibration methods showed to tackle matrix effects obtaining values between 69% and 85% for external matrix matched calibration and values from 76% to 111% and from 78% to 108% by analog and deuterated internal standard calibrations, respectively. Trueness of the method was studied using quality control material and certificated reference material (DON 1062±110μgkg(-1)). The values were compared by matrix-matched, analog internal standard (deepoxydeoxynivalenol (DOM-1)) and deuterated internal standard (DON-d(1)). |
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Authors:
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Josep Rubert; Kevin J James; Jordi Mañes; Carla Soler |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-23 |
Journal Detail:
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Title: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Volume: - ISSN: 1873-6351 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-4-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8207483 Medline TA: Food Chem Toxicol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012. Published by Elsevier Ltd. |
Affiliation:
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Department de Medicina Preventiva i Salut Pública, Facultat de Farmàcia, Universitat de València, Av. Vicent Andrés Estellés, 46100 Burjassot, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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