Document Detail


Study on intraluminal embolization with microcoils treating traumatic pseudoaneurysms in common carotid artery in rabbits.
MedLine Citation:
PMID:  15363218     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the long-term effect of endovascular occlusion with microcoils on traumatic pseudoaneurysms (TPAs) in the common carotid artery in rabbits. METHODS: TPAs in the right common carotid artery were surgically made in 16 rabbits. At 3-4 weeks after operation, the survived 12 models were randomly divided into a control group (n=3) with no treatment and an experimental group (n=9), in which TPAs were intraluminally embolized with microcoils and corresponding therapy was given. Three months after embolization, the TPAs were examined with digital subtraction angiography and pathology. RESULTS: The 3 rabbits in the control group all died of rupture of TPA. Among the 9 TPAs occluded with microcoils, 4 were completely occluded, 4 were partially occluded, and 1 was excluded due to the microcoils migrating into the parent artery. Three months after embolization, the 4 TPAs which were completely occluded remained obliterated as determined by digital subtraction angiographic findings. The parent artery remained unobstructed and the structure of the TPAs were replaced by a mass of scar tissues. The 4 TPAs which were partially occluded remained unruptured and the microcoils were compressed. CONCLUSIONS: The lumen in TPA can be completely occluded by microcoils and the parent artery is unblocked. Partial occlusion of the lumen can also prevent the rupture of TPA.
Authors:
Yun-Song Liu; Lian-Ting Ma; Zuo-Quan Wu
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Chinese journal of traumatology = Zhonghua chuang shang za zhi / Chinese Medical Association     Volume:  7     ISSN:  1008-1275     ISO Abbreviation:  Chin. J. Traumatol.     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-09-14     Completed Date:  2004-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100886162     Medline TA:  Chin J Traumatol     Country:  China    
Other Details:
Languages:  eng     Pagination:  266-70     Citation Subset:  IM    
Affiliation:
Department of Emergency, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, China. liuys_888@sohu.com
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MeSH Terms
Descriptor/Qualifier:
Aneurysm, False / pathology*,  radiography,  therapy*
Angiography
Animals
Biopsy, Needle
Carotid Artery, Common / pathology*
Disease Models, Animal
Embolization, Therapeutic / instrumentation*,  methods
Female
Immunohistochemistry
Male
Probability
Rabbits
Random Allocation
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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