| Study of interaction of long-chain n-alcohols with fluid DOPC bilayers by a lateral pressure sensitive fluorescence probe. | |
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MedLine Citation:
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PMID: 22781827 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The excimer 1,2-dipyrenedecanoyl-sn-glycero-3-phosphatidylcholine (dipy10PC) fluorescence probe was used to determine effects of aliphatic alcohols (CnH2n+1OH, n = 12-18 is the even number of carbons in alkyl chain) on fluid dioleoylphosphatidylcholine (DOPC) +dioleoylphosphatidylserine (DOPS) bilayers in multilamellar vesicles at molar ratio DOPC/DOPS = 24.7. The excimer to monomer fluorescence intensity ratio increases with the increase of CnH2n+1OH/DOPC molar ratio and decreases with the CnH2n+1OH alkyl chain length n at a constant CnH2n+1OH/DOPC = 0.4 molar ratio. These effects indicate changes in the bilayer lateral pressure on the level of pyrenyl moieties location. |
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Authors:
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Tatiana N Murugova; Mária Klacsová; Petra Pullmannová; Janka Karlovská; Pavol Balgavý |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: General physiology and biophysics Volume: 31 ISSN: 0231-5882 ISO Abbreviation: Gen. Physiol. Biophys. Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-07-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8400604 Medline TA: Gen Physiol Biophys Country: Slovakia |
Other Details:
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Languages: eng Pagination: 225-7 Citation Subset: IM |
Affiliation:
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Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, Dubna, Russia. murugova@jinr.ru. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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