|Study of food allergy in the Spanish population.|
|PMID: 17064647 Owner: NLM Status: MEDLINE|
|BACKGROUND: The aim of the study was to investigate the prevalence of food allergy in patients referred to our Allergy Unit and to evaluate the diagnostic methods used. METHODS: We selected 674 patients referred to the Allergy Unit of our hospital from May 2002 to October 2004. The prevalence of symptoms was determined by a standardized questionnaire, prick-prick test, and serum specific IgE. In a second phase, double-blind oral challenge tests were administered. RESULTS: Food allergy was found in 106 patients (15.7 %): 71 adults (67 %) and 35 children (33 %). The prevalence of food allergen sensitization was 14 % in adults and 20.8 % in children. A total of 89.6 % of the patients experienced symptoms immediately. Only 29.2 % the patients of sought medical attention and adrenaline was administered to five (16.1 %). The foods most frequently involved in allergic reactions were fruits (56.6 %) and tree nuts (22.6 %). The most common symptoms were oral allergy syndrome (46.2 %), urticaria (32.1 %), and anaphylaxis (14.2 %). Combining the results of the questionnaire with those of prick-prick tests in patients whose allergy was confirmed by double-blind, placebo-controlled food challenge (9.1 %) showed a sensitivity of 95.5 %, a negative predictive value of 96 %, a specificity of 75 % and a positive predictive value of 73 %. CONCLUSIONS: 1. The prevalence of food allergy in our sample was 9.1 %. 2. The foods most frequently involved in allergic reactions were fruits and tree nuts. 3. The most common symptoms were oral allergy syndrome, urticaria, and anaphylaxis. 4. Combining our questionnaire with in vivo tests allowed us to diagnose 75-96 % of patients with no food allergy and 95 % of food allergy patients.|
|M I Alvarado; M Pérez|
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|Type: Evaluation Studies; Journal Article|
|Title: Allergologia et immunopathologia Volume: 34 ISSN: 0301-0546 ISO Abbreviation: Allergol Immunopathol (Madr) Publication Date: 2006 Sep-Oct|
|Created Date: 2006-10-26 Completed Date: 2007-03-09 Revised Date: 2009-11-03|
Medline Journal Info:
|Nlm Unique ID: 0370073 Medline TA: Allergol Immunopathol (Madr) Country: Spain|
|Languages: eng Pagination: 185-93 Citation Subset: IM|
|Ciudad de Coria Hospital, Allergy Unit, Cáceres, Spain. firstname.lastname@example.org|
|APA/MLA Format Download EndNote Download BibTex|
Allergens / adverse effects, diagnostic use
Anaphylaxis / drug therapy, epidemiology, etiology
Angioedema / epidemiology, etiology
Epinephrine / therapeutic use
Food Hypersensitivity / diagnosis, drug therapy, epidemiology*, etiology
Fruit / adverse effects
Immunoglobulin E / blood
Nuts / adverse effects
Predictive Value of Tests
Sensitivity and Specificity
Spain / epidemiology
Stomatitis / epidemiology, etiology
Urticaria / epidemiology, etiology
|0/Allergens; 37341-29-0/Immunoglobulin E; 51-43-4/Epinephrine|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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