| Study of the efficacy of the black stone on envenomation by snake bite in the murine model. | |
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MedLine Citation:
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PMID: 17174999 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The black stone (BS) has been used since antiquity to treat envenomations. Since no actual clinical trial has ever been performed we used an experimental approach to evaluate its efficacy against the venoms of Bitis arietans, Echis ocellatus and Naja nigricollis. Local application of BS after intramuscular venom injection had no demonstrable effect on the outcome of envenomationa and it did not change the LD(50) of B. arietans venom. Our results show that, contrary to widespread belief, no efficacy to treat envenomation may be expected of the BS. |
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Authors:
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Jean-Philippe Chippaux; Blanca Ramos-Cerrillo; Roberto P Stock |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2006-11-16 |
Journal Detail:
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Title: Toxicon : official journal of the International Society on Toxinology Volume: 49 ISSN: 0041-0101 ISO Abbreviation: Toxicon Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-03-26 Completed Date: 2007-09-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1307333 Medline TA: Toxicon Country: England |
Other Details:
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Languages: eng Pagination: 717-20 Citation Subset: IM |
Affiliation:
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Institut de Recherche pour le Développement, La Paz, Bolivia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorption Animals Bone and Bones / chemistry* Lethal Dose 50 Medicine, Traditional* Mice Snake Bites / therapy* Snake Venoms / analysis, chemistry* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Snake Venoms |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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