Document Detail

Study on cytokines IL-2, IL-6, IL-10 in patients of chronic allergic rhinitis treated with acupuncture.
MedLine Citation:
PMID:  12125480     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To observe the plasmatic concentration of IL-6, IL-10 and IL-2 in the patient of chronic allergic rhinitis before and after acupuncture therapy. METHODS: Cytokine levels were determined before and after treatment in 30 healthy volunteers (Group A) and 90 patients of chronic allergic rhinitis (Group B) with an increased plasma IL-10 level. Group B was then divided into 3 subgroups: 30 patients treated with real acupuncture (Group B1); 30 patients treated with sham acupuncture (Group B2); 30 non-treated patients (Group B3). RESULTS: The allergic subjects of group B1, compared with controls, showed a significant reduction of IL-10 after a specific treatment with acupuncture (P < 0.05). On the other hand, in those patients treated with sham acupuncture (B2) as well as in non-treated patients (B3), the IL-10 values remained high and unchanged. There was a statistically significant change in IL-2 values at 24 hours (P < 0.05) after real acupuncture (Groups A, B1), however the values remained within normal ranges. The IL-6 do not change after therapy. CONCLUSION: The acupuncture treatment can reduce plasmatic level of IL-10 in chronic allergic rhinitis.
Filomena Bangrazi Petti; Aldo Liguori; Flora Ippoliti
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan / sponsored by All-China Association of Traditional Chinese Medicine, Academy of Traditional Chinese Medicine     Volume:  22     ISSN:  0255-2922     ISO Abbreviation:  J Tradit Chin Med     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-07-19     Completed Date:  2003-01-10     Revised Date:  2010-11-03    
Medline Journal Info:
Nlm Unique ID:  8211546     Medline TA:  J Tradit Chin Med     Country:  China    
Other Details:
Languages:  eng     Pagination:  104-11     Citation Subset:  IM    
Paracelso Institute, Body Corporate of Italian Ministry of Health, Chair of Social Medicine, School of Medicine La Sapienza University, Rome, Italy.
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MeSH Terms
Acupuncture Therapy*
CD4-Positive T-Lymphocytes / immunology
Interleukin-10 / blood*
Interleukin-2 / blood
Interleukin-6 / blood
Middle Aged
Rhinitis, Allergic, Perennial / blood,  therapy*
Reg. No./Substance:
0/Interleukin-2; 0/Interleukin-6; 130068-27-8/Interleukin-10

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