Document Detail

Study of the correlation between blood lipid levels and the severity of coronary atherosclerosis in a Chinese population sample.
MedLine Citation:
PMID:  17205916     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To investigate the relationship between blood lipid levels with severity of coronary artery atherosclerosis in a Chinese population sample. METHODS AND RESULTS: According to coronary angiography results, 363 patients (287 men and 76 women) with coronary artery atherosclerosis were divided into four groups: the single-vessel group (I, n = 125), the double-vessel group (II, n = 113), the triple-vessel group (III, n = 107) and the multi-vessel group (IV, n = 18). The severity of coronary artery atherosclerosis was quantified with a modified Gensini score on the basis of angiographic imaging. Serum triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), non-high density lipoprotein cholesterol (non-HDL-C) were measured before angiography in all groups. Levels of serum TC, LDL-C and non-HDL-C of the II, III and IV group were significantly higher than those of the I group (4.78 +/- 0.82 mmol/L and 4.87 +/- 1.50 mmol/L and 4.73 +/- 0.99 mmol/L vs. 4.38 +/- 0.93 mmol/L, 2.91 +/- 0.68 mmol/L and 2.74 +/- 1.23 mmol/L and 2.64 +/- 0.84 mmol/L vs. 2.30 +/- 0.77 mmol/L, 3.58 +/- 0.75 mmol/L and 3.59 +/- 1.41 mmol/L and 3.43 +/- 0.94 mmol/L vs. 3.17 +/- 0.91 mmol/L; p < 0.05); the mean levels of TC, LDL-C and non-HDL-C associated positively with the Gensini score. CONCLUSION: Serum lipid levels correlate positively with the severity of coronary artery atherosclerosis in a Chinese population sample. Patients with higher levels of serum TC, LDL-C and non-HDL-C have more severe coronary atherosclerosis, compared with those with low levels of serum TC, LDL-C and non-HDL-C.
Zhengming Jin; Yun Zhang; Junzhu Chen; Jianhua Zhu; Furong Zhang; Yuangang Qiu; Lili Zhao
Related Documents :
12086276 - Medical treatment and secondary prevention of coronary heart disease in general practic...
12771876 - Pretreatment with statins enhances myocardial protection during coronary revascularizat...
17095906 - The safety and efficacy of achieving very low ldl-cholesterol concentrations with high ...
19837406 - Association of the single nucleotide polymorphism rs599839 in the vicinity of the sorti...
2410706 - Cardioprotective effects of carbocromen in awake and anesthetized dogs with amitriptyli...
3628126 - Brain cardioembolism. issues in diagnosis and management.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cardiologica     Volume:  61     ISSN:  0001-5385     ISO Abbreviation:  Acta Cardiol     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2007-01-08     Completed Date:  2007-02-22     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  0370570     Medline TA:  Acta Cardiol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  603-6     Citation Subset:  IM    
Division of Cardiovascular Disease, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
China / epidemiology
Coronary Artery Disease / blood*,  epidemiology,  pathology*
Lipids / blood*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Heart rate variability in neurally mediated reflex syncope.
Next Document:  Cardiovascular risk factors in first-degree relatives of patients with premature coronary artery dis...