| Study of the correlation between blood lipid levels and the severity of coronary atherosclerosis in a Chinese population sample. | |
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MedLine Citation:
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PMID: 17205916 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the relationship between blood lipid levels with severity of coronary artery atherosclerosis in a Chinese population sample. METHODS AND RESULTS: According to coronary angiography results, 363 patients (287 men and 76 women) with coronary artery atherosclerosis were divided into four groups: the single-vessel group (I, n = 125), the double-vessel group (II, n = 113), the triple-vessel group (III, n = 107) and the multi-vessel group (IV, n = 18). The severity of coronary artery atherosclerosis was quantified with a modified Gensini score on the basis of angiographic imaging. Serum triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), non-high density lipoprotein cholesterol (non-HDL-C) were measured before angiography in all groups. Levels of serum TC, LDL-C and non-HDL-C of the II, III and IV group were significantly higher than those of the I group (4.78 +/- 0.82 mmol/L and 4.87 +/- 1.50 mmol/L and 4.73 +/- 0.99 mmol/L vs. 4.38 +/- 0.93 mmol/L, 2.91 +/- 0.68 mmol/L and 2.74 +/- 1.23 mmol/L and 2.64 +/- 0.84 mmol/L vs. 2.30 +/- 0.77 mmol/L, 3.58 +/- 0.75 mmol/L and 3.59 +/- 1.41 mmol/L and 3.43 +/- 0.94 mmol/L vs. 3.17 +/- 0.91 mmol/L; p < 0.05); the mean levels of TC, LDL-C and non-HDL-C associated positively with the Gensini score. CONCLUSION: Serum lipid levels correlate positively with the severity of coronary artery atherosclerosis in a Chinese population sample. Patients with higher levels of serum TC, LDL-C and non-HDL-C have more severe coronary atherosclerosis, compared with those with low levels of serum TC, LDL-C and non-HDL-C. |
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Authors:
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Zhengming Jin; Yun Zhang; Junzhu Chen; Jianhua Zhu; Furong Zhang; Yuangang Qiu; Lili Zhao |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta cardiologica Volume: 61 ISSN: 0001-5385 ISO Abbreviation: Acta Cardiol Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2007-01-08 Completed Date: 2007-02-22 Revised Date: 2009-11-03 |
Medline Journal Info:
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Nlm Unique ID: 0370570 Medline TA: Acta Cardiol Country: Belgium |
Other Details:
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Languages: eng Pagination: 603-6 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Disease, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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China
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epidemiology Coronary Artery Disease / blood*, epidemiology, pathology* Female Humans Lipids / blood* Male |
| Chemical | |
Reg. No./Substance:
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0/Lipids |
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