Document Detail

Study of clinical profile and antibiotic sensitivity pattern in culture positive typhoid fever cases.
MedLine Citation:
PMID:  16449839     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The present study was designed to analyze the clinical profile and antibiotic sensitivity pattern in the cases of culture positive typhoid fever. METHOD: The study was conducted over a period of 1 year. Total of 46 culture positive cases of Typhoid fever were included in the study. The sensitivity pattern of isolates from blood culture was recorded. The modes of presentation, clinical course, lab investigation reports were also recorded. RESULTS: Out of 46 cases, 33 (71.7%) were males and 13 (28.3%) were females. Average age of presentation was 26.17 years. Fever was present in all patients. Resistance of S .typhi to amoxycillin, chloramphenicol and co-trimoxazole were significantly high. Ciprofloxacin showed resistance in 2 (4.3%) cases. Sensitivity to ceftriaxone was 100% in our study. CONCLUSION: Typhoid fever is one of the most common health problem in Nepal. Various drugs are being used in the treatment of typhoid fever, in the mean time resistance to many of them are emerging. An appropriate antibiotic has to be initiated only after culture sensitivity in typhoid fever.
K C Mathura; D Chaudhary; R Simkhada; M Pradhan; P Shrestha; D L Gurubacharya
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kathmandu University medical journal (KUMJ)     Volume:  3     ISSN:  1812-2027     ISO Abbreviation:  -     Publication Date:    2005 Oct-Dec
Date Detail:
Created Date:  2006-02-01     Completed Date:  2007-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101215359     Medline TA:  Kathmandu Univ Med J (KUMJ)     Country:  Nepal    
Other Details:
Languages:  eng     Pagination:  376-9     Citation Subset:  IM    
Department of Medicine, Kathmandu Medical College Teaching Hospital.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use*
Microbial Sensitivity Tests
Salmonella typhi / drug effects*
Typhoid Fever / diagnosis*,  drug therapy,  microbiology
Reg. No./Substance:
0/Anti-Bacterial Agents

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