Document Detail

Study on the changes of thrombosis-associated factors in patients with coronary heart disease of turbidity-phlegm blocking syndrome.
MedLine Citation:
PMID:  19802536     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To preliminarily explore the relationship between thrombosis and its associated factors in patients with coronary heart disease (CHD) of turbidity-phlegm blocking syndrome (TPB), and to study its acting mechanism. METHODS: Plasma levels of thrombosis-associated factors, including Von Willebrand factor: (vWF), D-dimer, and fibrinogen (Fg), in 85 patients of CHD with TPB, 93 with CHD of non-TPD, and 89 healthy persons were detected and compared. RESULTS: Levels of the three factors were increased in all the CHD: patients, and were higher in TPB patients than in non-TPB patients (P<0.01 or P<0.05). CONCLUSION: The TPB: syndrome in CHD patients was closely related to the blood coagulation-fibrinolytic system; they might be in pre-thrombosis state, and the plasma levels of vWF, D-dimer, and Fg could be taken as the objective indices for thrombosis differentiation of TPB syndrome in CHD patients.
Yun-long Wang; Dong-qing An; Ning Ma; Meng Zhu; Hong-yan Sun
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Publication Detail:
Type:  Journal Article     Date:  2009-10-03
Journal Detail:
Title:  Chinese journal of integrative medicine     Volume:  15     ISSN:  1672-0415     ISO Abbreviation:  Chin J Integr Med     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-05     Completed Date:  2010-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101181180     Medline TA:  Chin J Integr Med     Country:  China    
Other Details:
Languages:  eng     Pagination:  337-40     Citation Subset:  IM    
Traditional Chinese Medicine College of Xinjiang Medical University, Urumiqi, China.
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MeSH Terms
Case-Control Studies
Coronary Disease / blood,  physiopathology*
Fibrin Fibrinogen Degradation Products / metabolism
Fibrinogen / analysis
Thrombosis / blood,  physiopathology*
von Willebrand Factor / metabolism
Reg. No./Substance:
0/Fibrin Fibrinogen Degradation Products; 0/fibrin fragment D; 0/von Willebrand Factor; 9001-32-5/Fibrinogen

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