Document Detail

Study on the Inter-zonal Migration of Airborne Infectious Particles in an Isolation Ward Using Benign Bacteria.
MedLine Citation:
PMID:  22725722     Owner:  NLM     Status:  Publisher    
Negative pressure isolation wards are essential infection control facilities against airborne transmissible diseases. Airborne infectious particles are supposed to be contained in the isolation room. However, negative pressure may break down by door opening action or by human movement. Understanding the inter-zonal transport of airborne infectious particles in the isolation wards can aid the design and operation strategy of isolation facilities. In this work, the inter-zonal migration of airborne infectious particles by human movement was studied experimentally in an isolation ward. Artificial saliva solution with benign E. coli bacteria was aerosolized to simulate bacterium-laden infectious particles. The inter-zonal migration of aerosolized bacteria was characterized by biological air sampling. Less than 1% of airborne infectious particles were transported to the higher pressure zone when door was closed. With human movement, 2.7% of the particles were transported from the anteroom to the corridor. From high-to-low pressure zones, as much as 20.7% of airborne infectious particles were migrated. Only a minimal amount of particles was transported from the corridor to the positive pressure Nurses' Station. Infection risk of tuberculosis of the healthcare workers and other occupants in the isolation wards were also assessed based on the measured migration ratios. Practical Implication:  Human movement is an important factor governing inter-zonal migration. It is the main cause of migration of airborne infectious particles to a relatively negative pressure zone. This study provides a set of experimentally obtained particle migration ratios by human movement. Other than serving as empirical data for further studies on the mechanics, these migration ratios can also be used to assess the infection risk for occupants in the isolation ward. © 2012 John Wiley & Sons A/S.
W T Leung; G N Sze-To; Christopher Y H Chao; Samuel C T Yu; Joseph K C Kwan
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-23
Journal Detail:
Title:  Indoor air     Volume:  -     ISSN:  1600-0668     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9423515     Medline TA:  Indoor Air     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 John Wiley & Sons A/S.
Department of Mechanical Engineering, The Hong Kong University of Science and Technology, Hong Kong. Building Energy Research Center, HKUST Fok Ying Tung Graduate School, The Hong Kong University of Science and Technology, Hong Kong. Division of Environment, The Hong Kong University of Science and Technology, Hong Kong. Health, Safety & Environment Office, The Hong Kong University of Science and Technology, Hong Kong.
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