Document Detail


The study of food addiction using animal models of binge eating.
MedLine Citation:
PMID:  20849896     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
This review summarizes evidence of "food addiction" using animal models of binge eating. In our model of sucrose bingeing, behavioral components of addiction are demonstrated and related to neurochemical changes that also occur with addictive drugs. Evidence supports the hypothesis that rats can become dependent and "addicted" to sucrose. Results obtained when animals binge on other palatable foods, including a fat-rich food, are described and suggest that increased body weight can occur. However, the characterization of an addiction-like behavioral profile in animals with binge access to fat requires further exploration in order to dissociate the effect of increased body weight from the diet or schedule of feeding.
Authors:
Nicole M Avena
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.     Date:  2010-09-16
Journal Detail:
Title:  Appetite     Volume:  55     ISSN:  1095-8304     ISO Abbreviation:  Appetite     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8006808     Medline TA:  Appetite     Country:  England    
Other Details:
Languages:  eng     Pagination:  734-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
University of Florida, Department of Psychiatry, Gainesville, 32608, United States. navena@ufl.edu
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
AA-12882/AA/NIAAA NIH HHS; DK-079793/DK/NIDDK NIH HHS; MH-65024/MH/NIMH NIH HHS

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