Document Detail

Study of 30 cases of histoplasmosis observed in the Mato Grosso do Sul State, Brazil.
MedLine Citation:
PMID:  17384818     Owner:  NLM     Status:  MEDLINE    
Thirty cases of histoplasmosis observed at the University Hospital of the Federal University of Mato Grosso do Sul (HU-UFMS) from January 1998 to December 2005 are reported. Most (83.3%) of the patients were men, average 33.4 years old, 63.3% of them were born and living in Mato Grosso do Sul and 83.3% presented AIDS as an underlying disease. In almost all cases (96.7%) the disease occurred in its disseminated form and the most frequent clinical manifestations were: fever (83.3%), weight loss (70.0%), cough (63.3%), hepatomegaly and splenomegaly (40.0%), and lymph node enlargement (36.7%). The laboratory diagnosis was obtained in 29 patients by isolation of Histoplasma capsulatum from various clinical specimens cultivated in Sabouraud dextrose and brain heart infusion agar and in 16 patients the fungus was observed by direct microscopy of Giemsa-stained smears. The observed mortality was 40%. This is the first report in the literature of the occurrence of histoplasmosis in Mato Grosso do Sul State.
Marilene Rodrigues Chang; Cleison Ledesma Taira; Anamaria Melo Miranda Paniago; Deborah Ledesma Taira; Rivaldo Venâncio Cunha; Bodo Wanke
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Revista do Instituto de Medicina Tropical de São Paulo     Volume:  49     ISSN:  0036-4665     ISO Abbreviation:  Rev. Inst. Med. Trop. Sao Paulo     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2007-03-26     Completed Date:  2007-07-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507484     Medline TA:  Rev Inst Med Trop Sao Paulo     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  37-9     Citation Subset:  IM    
Departamento de Farmácia e Bioquímica, Universidade Federal de Mato Grosso do SulMS, Brasil.
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MeSH Terms
AIDS-Related Opportunistic Infections / diagnosis*,  mortality
Brazil / epidemiology
Histoplasma / isolation & purification
Histoplasmosis / diagnosis*,  mortality
Middle Aged

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