Document Detail


Studies with a new cardioselective beta-blocker, metoprolol.
MedLine Citation:
PMID:  1032569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
These studies indicate that the cardioselective beta-adrenergic blocking drug metoprolol might be expected to be at least as effective for the treatment of arterial hypertension as propranolol. The difference in effect on the peripheral vascular bed may be of importance when acute increase of the blood adrenaline level occur, as in severe anxiety states. Experience in long-term studies in all kinds of patients with raised arterial pressure has confirmed that metoprolol is an active antihypertensive agent of similar potency to other beta-blocking agents.
Authors:
L Werkö; M Aurell; G Johnsson; R Sannerstedt; N Svedmyr
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Advances in clinical pharmacology     Volume:  11     ISSN:  0303-2671     ISO Abbreviation:  Adv Clin Pharmacol     Publication Date:  1976  
Date Detail:
Created Date:  1978-06-17     Completed Date:  1978-06-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0430232     Medline TA:  Adv Clin Pharmacol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  19-25     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Pressure / drug effects
Blood Vessels / drug effects
Bronchi / drug effects
Epinephrine / blood
Hemodynamics / drug effects
Humans
Hypertension / drug therapy*
Metoprolol / therapeutic use*
Propanolamines / therapeutic use*
Propranolol / therapeutic use
Renin / secretion
Chemical
Reg. No./Substance:
0/Propanolamines; 37350-58-6/Metoprolol; 51-43-4/Epinephrine; 525-66-6/Propranolol; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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