Document Detail


Studies on varicocele. 1. Submicroscopical and endocrinological features.
MedLine Citation:
PMID:  1764692     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this study we have selected a group of patients affected by a more or less severe condition of varicocele. After the evaluation of spermatogenesis and sperm function by electron microscopy we have demonstrated that the sperm malformations are mostly due to immaturity. Subsequently we have observed low FSH levels in the blood, concomitant with inhibin high contents, and we have studied Sertoli cells at submicroscopical level. In conclusion we suggest the following mode of action of varicocele in endocrinologically and spermatologically altered patients: varicocele----Sertoli cells----increased inhibin----hypophysis----decreased FSH----decreased testosterone----aberrant spermatogenesis----immature spermatozoa. The research will continue.
Authors:
B Baccetti; A G Burrini; S Capitani; G Collodel; G Di Cairano; P Piomboni; T Renieri; C Setacci
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of submicroscopic cytology and pathology     Volume:  23     ISSN:  1122-9497     ISO Abbreviation:  J. Submicrosc. Cytol. Pathol.     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-02-18     Completed Date:  1992-02-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804312     Medline TA:  J Submicrosc Cytol Pathol     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  659-65     Citation Subset:  IM    
Affiliation:
Institute of General Biology, University of Siena, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Follicle Stimulating Hormone / blood*
Humans
Inhibins / blood*
Luteinizing Hormone / blood
Male
Prolactin / blood
Semen / cytology
Sertoli Cells / physiology*
Sperm Count
Spermatozoa / physiology*,  ultrastructure
Thyrotropin / blood
Thyroxine / blood
Varicocele / blood,  diagnosis,  physiopathology*
Chemical
Reg. No./Substance:
57285-09-3/Inhibins; 7488-70-2/Thyroxine; 9002-62-4/Prolactin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone; 9002-71-5/Thyrotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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