Document Detail


STUDIES ON THE SYNDROME OF FAT EMBOLIZATION.
MedLine Citation:
PMID:  14158953     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three patients, all of whom were well-muscled young adult males who had suffered fractures of long bones, were studied by means of measurement of ventilatory function and arterial blood gases. They had degrees of mental change varying from mild confusion to stupor. Anemia, hypocalcemia, skin petechiae and radiologic pulmonary infiltrates were demonstrated in all three.In the absence of any clinical cyanosis, profound arterial O(2) desaturation was demonstrated in all. Physiologic studies indicated that the desaturation was the result of a diffusion defect early in the course of the syndrome and later from venous admixture. The lungs were stiff and the work of breathing was increased. The anemia appeared to be hemolytic in type.It is suggested that anemia, hypocalcemia and arterial O(2) desaturation may contribute significantly to the cerebral symptomatology associated with the syndrome of fat embolization.
Authors:
B J SPROULE; J L BRADY; J A GILBERT
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  90     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1964 May 
Date Detail:
Created Date:  1964-10-01     Completed Date:  1996-12-01     Revised Date:  2010-06-22    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1243-7     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Anemia, Hemolytic*
Blood Chemical Analysis*
Blood Gas Analysis*
Central Nervous System Diseases*
Embolism, Fat*
Femoral Fractures*
Hypocalcemia*
Lipid Metabolism*
Oximetry*
Respiratory Function Tests*
Tibial Fractures*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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