Document Detail

Studies on sister chromatid exchanges in peripheral lymphocytes of spray painters.
MedLine Citation:
PMID:  11934014     Owner:  NLM     Status:  MEDLINE    
In a comparative study of sister chromatid exchanges (SCEs) in cultured lymphocytes, we evaluated the genotoxic risk in 104 male spray painters employed in repair workshops in Chennai City, India, and 50 matched healthy, unexposed controls. We found a higher frequency of SCEs among painters (3.74 +/- 0.11, mean +/- SE) than among controls (2.15 +/- 0.08), and among smoking painters (4.03 +/- 0.21) than among nonsmoking painters (3.55 +/- 0.13), with no significant difference in controls (smokers: 2.1 +/- 0.2; nonsmokers: 2.2 +/- 0.1). Alcoholism did not contribute to an increased SCE frequency. Stepwise multiple linear regression analysis on painters showed that duration of service, smoking, and alcoholism significantly affected SCE scores and explained the 14% variation observed.
Palanivel Gajalakshmi; Protima Mallick; Perumal Venkatesan; Sathyaveedu Thiagarjan Santhiya; Arabandi Ramesh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer     Volume:  21     ISSN:  0731-8898     ISO Abbreviation:  J. Environ. Pathol. Toxicol. Oncol.     Publication Date:  2002  
Date Detail:
Created Date:  2002-04-05     Completed Date:  2002-04-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501420     Medline TA:  J Environ Pathol Toxicol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  63-5     Citation Subset:  IM    
Department of Genetics, Dr. ALMPGIBMS, University of Madras, Taramani Chennai, India.
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MeSH Terms
Alcoholism / complications
Inhalation Exposure*
Middle Aged
Occupational Exposure*
Regression Analysis
Sister Chromatid Exchange*
Smoking / adverse effects
Time Factors

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