Document Detail

Studies on preparation of a tick-borne encephalitis (TBE) vaccine from the Skalica strain.
MedLine Citation:
PMID:  2874729     Owner:  NLM     Status:  MEDLINE    
Diethylether-treated vaccine against tick-borne encephalitis (TBE) represents a new type vaccine consisting of lipid-free and antigenically efficient components instead of whole virus particles. The TBE virus strain designated Skalica was used for vaccine preparation. This strain is thermosensitive, produces small plaques under agar overlay, is nonpathogenic for adult white mice following subcutaneous (s.c.) application and causes threshold viraemia in host animals. The vaccine was harmless and immunogenic as evidenced by experiments on white mice. Antibodies to TBE virus strain Ir 13 present in human healthy population of a natural TBE focus showed similar levels when tested with the Skalica strain. The Skalica virus strain can be recommended for preparation of the vaccine against TBE.
M Gresíková; M Sekeyová; K Marcinka; F Ciampor
Related Documents :
23728029 - Hepatitis b knowledge, screening, and vaccination among hmong americans.
16990149 - Infectious bronchitis virus: s1 gene characteristics of vaccines used in china and effi...
25092439 - Combination of the two schistosomal antigens sm14 and sm29 elicits significant protecti...
3029289 - Construction and characterization of deletion mutants of pseudorabies virus: a new gene...
23306359 - A novel therapeutic hepatitis b vaccine induces cellular and humoral immune responses a...
20402229 - Evaluation of streptococcus iniae killed bacterin and live attenuated vaccines in hybri...
9230599 - Response to purified chick embryo cell rabies vaccine administered intradermally for po...
7729379 - Phagolysosomal morphology and dissolution of cobalt oxide particles by human and rabbit...
11240779 - The use of vaccines in treating cervical cancer: present status and future prospects.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta virologica     Volume:  30     ISSN:  0001-723X     ISO Abbreviation:  Acta Virol.     Publication Date:  1986 May 
Date Detail:
Created Date:  1986-09-23     Completed Date:  1986-09-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370401     Medline TA:  Acta Virol     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  243-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antibodies, Viral / biosynthesis*
Cells, Cultured
Chick Embryo
Electrophoresis, Polyacrylamide Gel
Encephalitis Viruses, Tick-Borne / immunology*,  ultrastructure
Encephalitis, Tick-Borne / immunology*
Ether, Ethyl
Hemagglutination Inhibition Tests
Microscopy, Electron
Vaccines, Attenuated / immunology
Viral Vaccines / immunology*
Reg. No./Substance:
0/Antibodies, Viral; 0/Vaccines, Attenuated; 0/Viral Vaccines; 60-29-7/Ether, Ethyl

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Contribution to rapid diagnosis of infectious mononucleosis.
Next Document:  Effect of maternal varicella-zoster virus infection on the outcome of pregnancy and the analysis of ...