Document Detail


Studies on plasma endothelin changes in varicocele patients.
MedLine Citation:
PMID:  11250786     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To investigate the possible role endothelin may play in the pathogenesis of varicocele and varicocele-induced infertility. METHODS: In varicocele patients, radioimmunoassay is used to determine the blood endothelin concentration in the spermatic vein and the antecubital vein separately. RESULTS: The blood endothelin concentration of the spermatic vein (66.8 +/- 23.5 pg/mL) was significantly higher (P < 0.05) than that of the antecubital vein (55.3 +/- 25.3 pg/mL). The endothelin concentration in the spermatic vein in Grade II varicocele patients was not significantly different from that in Grade III patients (P = 0.87). CONCLUSION: The higher blood endothelin level in the spermatic vein may indicate the involvement of endothelin in the pathophysiology of varicocele and varicocele-induced infertility.
Authors:
Q Q Xu; J C Zhu; H Jiang; X F Wang; S K Hou; Q L Liu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Asian journal of andrology     Volume:  1     ISSN:  1008-682X     ISO Abbreviation:  Asian J. Androl.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2001-06-08     Completed Date:  2001-06-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100942132     Medline TA:  Asian J Androl     Country:  China    
Other Details:
Languages:  eng     Pagination:  159-60     Citation Subset:  IM    
Affiliation:
Department of Urology, People's Hospital, Beijing Medical University, Beijing 100011, China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Endothelins / blood*
Humans
Infertility, Male
Male
Radioimmunoassay
Varicocele / blood*
Chemical
Reg. No./Substance:
0/Endothelins

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