| Studies on ornithine decarboxylase from liver, kidney and tumoral tissues during activity decay following cycloheximide administration. | |
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MedLine Citation:
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PMID: 3621358 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have studied the activity, thiol-dependency and Km of ornithine decarboxylase (ODC) from the following sources: liver of rats subjected to partial hepatectomy or administered thioacetamide, the rat 3924A Morris hepatoma, the rat AH130 Yoshida ascites hepatoma, a mouse transplantable mammary carcinoma and kidney of rats administered testosterone propionate. In order to detect possible changes occurring during in vivo ageing of this enzyme we inhibited protein synthesis with cycloheximide. A gradual decrease of Km during ageing was observed in ODC from liver. |
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Authors:
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E Gravela; M F Zuretti; O Brossa |
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Publication Detail:
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Type: In Vitro; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cell biology international reports Volume: 11 ISSN: 0309-1651 ISO Abbreviation: Cell Biol. Int. Rep. Publication Date: 1987 Aug |
Date Detail:
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Created Date: 1987-10-20 Completed Date: 1987-10-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7708050 Medline TA: Cell Biol Int Rep Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 573-82 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cycloheximide / pharmacology* Female Hepatectomy Kidney / enzymology* Liver / enzymology* Liver Neoplasms, Experimental / enzymology Liver Regeneration Male Mammary Neoplasms, Experimental / enzymology Mice Neoplasms, Experimental / enzymology* Ornithine Decarboxylase / metabolism* Rats Rats, Inbred Strains Thioacetamide / pharmacology |
| Chemical | |
Reg. No./Substance:
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62-55-5/Thioacetamide; 66-81-9/Cycloheximide; EC 4.1.1.17/Ornithine Decarboxylase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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