Document Detail

Studies on maternal transmission of scrapie in sheep by embryo transfer.
MedLine Citation:
PMID:  1350694     Owner:  NLM     Status:  MEDLINE    
The technique of embryo transfer was used to investigate the maternal transmission of scrapie in sheep. Embryo donor ewes were experimentally infected with scrapie (all eventually developing the disease) and artificially inseminated six months later with semen from an uninfected scrapie-susceptible ram. Embryos were harvested five and six days after insemination and transferred by laparoscopy, unwashed, into recipient ewes which had been genetically selected for very low susceptibility to scrapie. Six of the 26 lambs born to these recipients developed scrapie.
J D Foster; W A McKelvey; M J Mylne; A Williams; N Hunter; J Hope; H Fraser
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  130     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  1992 Apr 
Date Detail:
Created Date:  1992-06-29     Completed Date:  1992-06-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  341-3     Citation Subset:  IM    
Institute for Animal Health, Edinburgh.
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MeSH Terms
Brain Diseases / diagnosis,  microbiology,  veterinary*
Embryo Transfer / methods,  veterinary*
Insemination, Artificial / veterinary
Ovary / microbiology
Polymorphism, Restriction Fragment Length
Pregnancy Complications, Infectious / microbiology,  veterinary*
Scrapie / diagnosis,  microbiology,  transmission*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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