Document Detail

Studies of intrastromal corneal ring segments for the correction of low to moderate myopic refractive errors.
MedLine Citation:
PMID:  10703146     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Intrastromal corneal ring segments (ICRS) were investigated for safety and reliability in the correction of low to moderate myopic refractive errors. METHODS: Initially, 74 patients with spherical equivalent refractive errors between -1.00 and -4.25 diopters (D) received the ICRS in 1 eye. After 6 months, 51 of these patients received the ICRS in the contralateral eye. The total number of eyes investigated was 125. The outcome measures were uncorrected and best-corrected visual acuity, predictability and stability of the refraction, refractive astigmatism, contrast sensitivity, and endothelial cell morphology. RESULTS: The 89 eyes with 12-month follow-up showed significant improvement with uncorrected visual acuities of 20/16 or better in 37%, 20/20 or better in 62%, and 20/40 or better in 97%. Cycloplegic refraction spherical equivalents showed that 68% of the eyes were within +/- 0.50 D and 90% within +/- 1.00 D of the intended correction. Refractive stability was present by 3 months after the surgery. Only 1 patients had a loss greater than 2 lines or 10 letters of best spectacle-corrected visual acuity, but the patient's acuity was 20/20. Refractive cylinder, contrast sensitivity, and endothelial cell morphology were not adversely affected. The ICRS was removed from the eyes of 6 patients. Three removals were prompted by glare and double images occurring at night; 3 were for nonmedical reasons. All patients returned to within +/- 1.00 D of their preoperative refractive spherical equivalent, and no patients lost more than 1 line of best corrected visual acuity by 3 months after ICRS removal. CONCLUSION: The ICRS safely and reliably corrects myopic refractive errors between -1.00 and -4.50 D.
D J Schanzlin
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Publication Detail:
Type:  Clinical Trial; Clinical Trial, Phase II; Clinical Trial, Phase III; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Transactions of the American Ophthalmological Society     Volume:  97     ISSN:  0065-9533     ISO Abbreviation:  Trans Am Ophthalmol Soc     Publication Date:  1999  
Date Detail:
Created Date:  2000-03-21     Completed Date:  2000-03-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7506106     Medline TA:  Trans Am Ophthalmol Soc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  815-90     Citation Subset:  IM    
Shiley Eye Center, University of California, San Diego, USA.
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MeSH Terms
Cell Count
Cornea / cytology,  surgery*
Endothelium, Corneal / pathology
Middle Aged
Myopia / surgery*
Prospective Studies
Prostheses and Implants
Prosthesis Implantation*
Refraction, Ocular
Treatment Outcome
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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