Document Detail


Studies on the in vivo-action of leupeptin on the nitrogen retention in rats.
MedLine Citation:
PMID:  616737     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A daily s.c. injection of 0.5 mg leupeptin for 7 days does not influence the digestibility of food-N but seems to improve the N-retention. A daily injection of 1.0 mg leupeptin for 14 days is without influence on the digestibility of N, too, but the N-retention was decreased. At this leupeptin level the half-lives of intestinal proteins were prolonged. The data indicate the possibility to influence the N-retention using leupeptin.
Authors:
O Simon; P Bohley; R Münchmeyer; H Bergner; C Hückel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta biologica et medica Germanica     Volume:  36     ISSN:  0001-5318     ISO Abbreviation:  Acta Biol. Med. Ger.     Publication Date:  1977  
Date Detail:
Created Date:  1978-12-02     Completed Date:  1978-12-02     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0370276     Medline TA:  Acta Biol Med Ger     Country:  GERMANY, EAST    
Other Details:
Languages:  eng     Pagination:  1923-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Dietary Proteins
Half-Life
Intestine, Large / metabolism
Intestine, Small / metabolism
Kinetics
Leupeptins / pharmacology*
Nitrogen / metabolism*
Oligopeptides / pharmacology*
Proteins / metabolism*
Rats
Chemical
Reg. No./Substance:
0/Dietary Proteins; 0/Leupeptins; 0/Oligopeptides; 0/Proteins; 7727-37-9/Nitrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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