Document Detail

Studies in relation to endocrine exophthalmos: the biochemical composition of human retrobulbar connective tissue.
MedLine Citation:
PMID:  130249     Owner:  NLM     Status:  MEDLINE    
As part of studies on the pathogenesis of exophthalmos of Graves' disease, the biochemical composition of human retrobulbar tissue was investigated. The connective tissue was composed of 72.7% lipid, 23.8% water and 3.5% dried defatted tissue. Total tissue glycosaminoglycan (GAG) amounted to 0.18% of dried defatted tissue. Approximately 27% of the total hexosamine and 19% of the total tissue galactosamine were recovered in the GAG fraction. Cellulose microcolumn fractionation of GAG showed that the hyaluronic acid and dermatan sulfate were the two major GAG species.
A P Singh; M Nikiforuk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experientia     Volume:  32     ISSN:  0014-4754     ISO Abbreviation:  Experientia     Publication Date:  1976 Mar 
Date Detail:
Created Date:  1976-06-02     Completed Date:  1976-06-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0376547     Medline TA:  Experientia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  395-6     Citation Subset:  IM    
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MeSH Terms
Connective Tissue / analysis*
Glycosaminoglycans / analysis
Hexosamines / analysis
Lipids / analysis
Middle Aged
Proteins / analysis
Uronic Acids / analysis
Water / analysis
Reg. No./Substance:
0/Glycosaminoglycans; 0/Hexosamines; 0/Lipids; 0/Proteins; 0/Uronic Acids; 7732-18-5/Water

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